CAS NO.:64638-07-9 Dimethoxybromoamphetamine ;DOB C11H16BrNO2 Recreational Club Clinical Composite Psychoactive Aphrodisiac Designer Drug

Dimethoxybromoamphetamine (DOB), also known as brolamfetamine and bromo-DMA.



Detail:


        Dimethoxybromoamphetamine (DOB), also known as brolamfetamine  and bromo-DMA, is a psychedelic drug and substituted amphetamine of the phenethylamine class of compounds. DOB was first synthesized by Alexander Shulgin in 1967.

Chemistry:



        The full name of the chemical is 2,5-dimethoxy-4-bromoamphetamine. DOB has a stereocenter and R-(–)-DOB is the eutomer. This is an important finding as it is suggestive that it is targeting different receptors relative to most other phenethylamines (e.g. MDMA) where the R-isomer serves as the distomer. The toxicity of DOB is not fully known, although high doses may cause serious vasoconstriction of the extremities. DOB is one of the most potent compounds in PiHKAL; while the active dose is similar to that of DOI, another psychedelic amphetamine, DOB has been shown to have a higher efficacy in triggering downstream effects mediated by 5-HT2 receptors, making it likely to be slightly more dangerous than DOI in overdose, due to greater vasoconstrictive action. Omission of the amphetamine related α-methyl leads to 2C-B, a compound that possesses a lower affinity for the 5-HT2A receptor and is a weaker receptor agonist which results in drastically reduced vasoconstriction.


Pharmacology:

        DOB is a 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are mediated by its agonistic properties at the 5-HT2A receptor. Due to its selectivity, DOB is often used in scientific research when studying the 5-HT2 receptor subfamily. It is an agonist of human TAAR1.



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Packing 1-4

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Purity

Pure

Appearance:

Conform

Date of delivery:

Within 48 hours when you finished the payment

Sales territory:

All over the world

Stock:

Enough

Transportation insurance:

Yes

Shipping origin:

HongKong

Synthesis of cycle:

2-7 days





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