Detail:
3-Hydroxyphencyclidine (3-HO-PCP) is a dissociative hallucinogen of the arylcyclohexylamine class related to phencyclidine (PCP) that has been sold online as a designer drug.
Pharmacology:
3-HO-PCP acts as a high-affinity uncompetitive antagonist of the NMDA receptor via the dizocilpine (MK-801) site (Ki = 30 nM). It has much higher affinity than PCP for this site (Ki = 250 nM, for comparison; 8-fold difference). The drug also has high affinity for the μ-opioid receptor (MOR) (Ki = 39–60 nM), the κ-opioid receptor (KOR) (Ki = 140 nM), and the sigma σ1 receptor (Ki = 42 nM; IC50 = 19 nM), whereas it has only low affinity for the δ-opioid receptor (Ki = 2,300 nM). The high affinity of 3-HO-PCP for opioid receptors is unique among arylcyclohexylamines and is in contrast to PCP, which has only very low affinity for the MOR (Ki = 11,000–26,000 nM; 282- to 433-fold difference) and the other opioid receptors (Ki = 4,100 nM for the KOR and 73,000 nM for the DOR).
Although it was hypothesized that 3-HO-PCP might be a metabolite of PCP in humans, there is no evidence that this is the case.
Chemistry:
3-HO-PCP is an arylcyclohexylamine. Close analogues of 3-HO-PCP include PCP, 3-MeO-PCP, 4-MeO-PCP, 3-MeO-PCMo, and somewhat more distantly ketamine, methoxyketamine, 3-MeO-PCE, and methoxetamine.
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Packing：
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Packing 1-4
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Shipping：
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Shipping 1-4
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Payment：
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Bitcoin;WU;MG;Bank
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Purity：
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Pure
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Appearance:
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Conform
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Date of delivery:
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Within 48 hours when you finished the payment
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Sales territory:
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All over the world
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Stock:
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Enough
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Transportation insurance:
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Yes
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Shipping origin:
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HongKong
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Synthesis of cycle:
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2-7 days
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Application range：
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Recreational Club Drugs;Chemistry Experiment；psychedelic ；Reagent and Other
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Manufacturer:
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Universal drugs Lab
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Expiration date：
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5 Years
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