L-GLUTATHIONE REDUCED (GSH) 70-18-8

L-GLUTATHIONE REDUCED (GSH) 70-18-8



Product Information


Glutathione is an antioxidant that helps protecting cells from reactive oxygen species such as free radicals and peroxides. By acting as an electron donor, glutathione reduces any disulfide bond formed within cytoplasmic proteins to cysteines. Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form, glutathione reductase, is constitutively active and inducible upon oxidative stress. In fact, the ratio of reduced glutathione to oxidized glutathione within cells is often used scientifically as a measure of cellular toxicity.


Product name
L-Glutathione Reduced
Molecular Formula
C20H32N6O12S2
Molecular Weight
612.63
CAS No.
70-18-8
ENIECE No
200-725-4
Appearance
white powder

Specifications

1. Food /cosmetic grade (≥98% , USP35 /USP37/USP41) ;

2.Pharmaceutical /injection grade ( ≥98% ,EP7) ;


Usage


L-Glutathione Reduced is widely used in Pharmaceuticals, Nutraceuticals,Health functional foods, Dietary supplements, Skin-Whitening products, Cosmetic etc

The regular dosage form: Lyophilized Powder for Injection,Tablets,Capsules, Eye drops etc.


a. Daily nutraceuticals & Dietary supplement


1. Anti-aging, antioxidant, maintain skin vigor and luster

2. Whitening skin: restraining the melanin

3. Improve immunity: enhance immune cells function effectively prevent viruses


b. Drug treatment and prevention


1. Protect liver: prevention & treatment of liver diseases

2. Detoxification: drugs and other kinds of poisoning auxiliary treatments,helpful for excreting toxins.

3. Prevention and treatment of eye diseases

4. Auxiliary treatment of diabetes


Our advantage


1. Technology from Japan, equipment from USA, EU and JANPAN, standard GMP workshop.

2. Fermentation process, using the non-GMO yeast, ensure product safety and high purity

3. Non-animal origin, Kosher, Halal and HACCP certificates.

4. Large capacity(200MT/year); have stock ;quick delivery time

5. We can provide GMP/DMF documents


COA of L-Glutathione Reduced (USP41)

Test Item

Specification

Result

Analytical Method Reference

Appearance

White or almost white crystalline powder

White crystalline powder

Visual

Appearance of solution

(10% w/v in water)

Clear and colorless

Complies

Visual

Bulk Density

≥0.50 g/ml

0.52 g/ml

In-house

Tapped Density

≥0.60 g/ml

0.65 g/ml

In-house

Particle Size

100% thru mesh 80

Complies

Mesh screen

Identification

S.O.R.

-15.5° ~ -17.5°

-16.0°

USP <781S>

Infrared

Positive

Positive

USP <197K>

Related

L-glutathione oxidized

≤1.5%

0.3%

Glutathione USP monograph

Total impurities

≤2.0%

1.5%

Glutathione USP monograph

Assay(dry basis)

98.0% to 101.0%

100.3%

Glutathione USP monograph

Loss on drying(3 h at 105℃)

≤0.5%

0.3%

USP <731>

Residue on Ignition

≤0.1%

<0.1%

USP <281>

Ammonium

≤200ppm

﹤200ppm

Glutathione USP monograph

Chloride

≤200ppm

﹤200ppm

USP <221>

Sulfate

≤300ppm

﹤300ppm

USP <221>

Iron

≤10ppm

﹤10ppm

USP <241>

Arsenic

≤1ppm

<1ppm

AFS

Cadmium

≤1ppm

<1ppm

AAS

Lead

≤1ppm

<1ppm

AAS

Mercury

≤1ppm

<1ppm

AFS

Heavy metals

≤10ppm

<10ppm

USP <231>Method I

Total Plate Count

≤1000 cfu/g

<10 cfu/g

USP <61>

Yeast and Mold

≤100 cfu/g

25 cfu/g

USP <61>

Coliforms

≤30 cfu/g

<10 cfu/g

USP <61>

E. Coli

Negative/g

Negative

USP <62>

Salmonella

Negative/10g

Negative

USP <62>

Staphylococcus Aureus

Negative/g

Negative

USP <62>


Conclusion: Complies with the USP 41 standards.



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