Product Information


Product name

Mupirocin

Molecular Formula

C26H44O9

Molecular Weight

500.6222

CAS No.

12650-69-0

Quality Standard

GMP / USP34 / EP6

Appearance

white powder


COA of Mupirocin


ITEMS

SPECIFICATIONS

RESULT

Appearance

A white or off-white powder

Conforms

Identification(A,B)

Positive

Conforms

Specific Optical Rotation

-20°~ -16°

-18°

Impurity C

Not more than 2.5%

1.6%

Individual impurity

Not more than 1.0%

Conforms

Total impurities

Not more than 4.5%

3.5%

Chlorides

Not more than 0.5%

Conforms

PH

3.0~4.5

3.6

Water

Not more than 1.0%

0.1%

Residual Solvents

Ethyl Acetate

Not more than 500 ppm

Not deteced

Isobutyl Acetate

Not more than 5000 ppm

5

Heptane

Not more than 500 ppm

2

Acetone

Not more than 3000 ppm

15

Assay

93.0-102.0%

98.1%


Usage



Mupirocin is a topical antibiotic for external use, which is a substance produced by Pseudomonas fluorescens culture fluid, namely Pseudomonas A. Its antibacterial effect is mainly by reversibly combining with isoleucine transfer RNA synthetase, preventing isoleucine infiltration, and stopping the synthesis of isoleucine-containing protein in cells to play a bactericidal or bacteriostatic role. Mupirocin shows bacteriostatic effect at very low concentration and bactericidal effect at high concentration. Mupirocin is highly sensitive to various Gram-positive cocci related to skin infections, especially Staphylococcus and Streptococcus. It is also effective against resistant Staphylococcus aureus; Neisseria gonorrhoeae has some antibacterial effect; it is not sensitive to most anaerobic bacteria and normal skin flora. The incidence of drug-resistant mutants in vitro is very low.

We are professional mupirocin manufacturer and we have mupirocin for sale  including mupirocin for acne, mupirocin for ringworm and mupirocin for eczema.



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